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Flutrimazole CAS Registry Number: 119006-77-8 氟曲马唑

CAS Name: 1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole
Additional Names: 1-[o-fluoro-a-(p-fluorophenyl)-a-phenylbenzyl]imidazoleTrademarks: Micetal (Uriach)
Percent Composition: C 76.29%, H 4.66%, F 10.97%, N 8.09%

📌 参考资料/链接：
Literature References: Prepn: J. Bartroli, M. Anguita, EP 352352; eidem, US 5149707 (1990, 1992 both to Uriach). Series of articles on synthesis, antifungal activity, pharmacokinetics: Arzneim.-Forsch. 42, 832-863 (1992). Toxicity study: M. L. Vericat et al., ibid. 841. Clinical trial in dermatomycoses: O. Binet et al., Mycoses 37, 455 (1994).

📄 详细内容

Properties: Crystals from acetonitrile, mp 164-167°. Also reported as white solid, mp 161-163°. LD50 in male, female mice, male, female rats (mg/kg): 1000, 1000, 808, 1214 orally; 2000, 2000, 1079, 1446 i.p. (Vericat).
Melting point: mp 164-167°; mp 161-163°
Toxicity data: LD50 in male, female mice, male, female rats (mg/kg): 1000, 1000, 808, 1214 orally; 2000, 2000, 1079, 1446 i.p. (Vericat)
Therap-Cat: Antifungal (topical).
Keywords: Antifungal (Synthetic); Imidazoles.
产品链接: 119006-77-8››

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