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Carticaine CAS Registry Number: 23964-58-1 阿替卡因

CAS Name: 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester
Additional Names: 3-propylamino-a-propionylamino-2-carbomethoxy-4-methylthiophene; methyl 4-methyl-3-(2-propylaminopropionamido)thiophene-2-carboxylate; articaine
Percent Composition: C 54.91%, H 7.09%, N 9.85%, O 16.88%, S 11.28%

📌 参考资料/链接：
Literature References: Prepn: H. Ruschig et al., ZA 6804265; eidem, US 3855243 (1969, 1974 both to Farbwerke Hoechst). Pharmacological studies: R. Muschaweck, R. Rippel, Prakt. Anaesth. 9, 135 (1974); H. Hofer et al., ibid. 157; A. Den Hertog, Eur. J. Pharmacol. 26, 175 (1974). Toxicity studies: C. Baeder et al., Prakt. Anaesth. 9, 147 (1974). Mechanism of action: U. Borchard, H. Drouin, Eur. J. Pharmacol. 62, 73 (1980). Review: H. Schneider, Schweiz. Monatsschr. Zahnheilkd. 86, 1188-1194 (1976).

📄 详细内容

Properties: bp0.3 162-167°.
Boiling point: bp0.3 162-167°
Derivative Type: Hydrochloride
CAS Registry Number: 23964-57-0Trademarks: Ultracain (HMR)
Percent Composition: C 48.67%, H 6.60%, N 8.73%, O 14.96%, S 9.99%, Cl 11.05%
Properties: White, fine crystals, mp 177-178°. LD50 i.v. in mice: 37 mg/kg (Muschaweck, Rippel).
Melting point: mp 177-178°
Toxicity data: LD50 i.v. in mice: 37 mg/kg (Muschaweck, Rippel)
Therap-Cat: Anesthetic (local).
Keywords: Anesthetic (Local).
产品链接: 23964-58-1››

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