Glibornuride CAS Registry Number: 26944-48-9 格列波脲
CAS Name: [1S-(endo,endo)]-N-[[(3-Hydroxy-4,7,7-trimethylbicyclo[2.2.1]hept-2-yl)amino]carbonyl]-4-methylbenzenesulfonamide
Additional Names: (1R,2R,3S,4S)-1-(2-hydroxy-3-bornyl)-3-(p-tolylsulfonyl)urea; D-3-endo-p-tosylureidoborneol; 1-(p-tolylsulfonyl)-3-(2-endo-hydroxy-3-endo-D-bornyl)ureaTrademarks: Gluborid (Grñenthal); Glutril (Roche)
Percent Composition: C 58.99%, H 7.15%, N 7.64%, O 17.46%, S 8.75%
📌 参考资料/链接：
Literature References: Prepn: H. Bretschneider et al., Monatsh. Chem. 100, 2133 (1969). See also: eidem, ZA 6706161; eidem, US 3770761; eidem, ZA 6902395; eidem, US 3654357 (1968, 1973, 1969, 1972, all to Hoffmann-La Roche). Comprehensive review of pharmacology: Arzneim.-Forsch. 22, 2153-2222 (1972).
📄 详细内容
Properties: Crystals, mp 192-195° (ethanol-water); also reported as 195-198°. [a]D +63.8° (ethanol).
Melting point: mp 192-195° (ethanol-water); also reported as 195-198°
Optical Rotation: [a]D +63.8° (ethanol)
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic; Sulfonylurea Derivatives.
产品链接: 26944-48-9››