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Clobenztropine CAS Registry Number: 5627-46-3 氯苯托品


CAS Name: 3-[(4-Chlorophenyl)phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane
Additional Names: 3-[(p-chloro-a-phenylbenzyl)oxy]tropane; tropine 4-chlorobenzhydryl ether
Trademarks: Teprin (Endo)
Percent Composition: C 73.78%, H 7.08%, Cl 10.37%, N 4.10%, O 4.68%
📌 参考资料/链接:
Literature References: Prepn: Fromer, US 2799680 (1957); Nield, Bosch, US 2782200 (1957 to Schenley Labs.).

📄 详细内容


Derivative Type: Hydrochloride
Percent Composition: C 66.67%, H 6.66%, Cl 18.74%, N 3.70%, O 4.23%
Properties: Crystals from isopropanol, mp 215-217°. Sol in water, ethanol. Practically insol in acetone, benzene, ether.
Melting point: mp 215-217°
Derivative Type: Hydrobromide
Percent Composition: C 59.66%, H 5.96%, Cl 8.39%, N 3.31%, O 3.78%, Br 18.90%
Properties: mp 197-200°. Sol in hot water, hot ethanol. Practically insol in acetone, benzene, ether.
Melting point: mp 197-200°
Derivative Type: Methobromide
Percent Composition: C 60.49%, H 6.23%, Cl 8.12%, N 3.21%, O 3.66%, Br 18.29%
Properties: mp 245-248°. Sol in hot water, in ethanol. Practically insol in acetone, benzene, ether.
Melting point: mp 245-248°
Derivative Type: Methochloride
Percent Composition: C 67.35%, H 6.94%, Cl 18.07%, N 3.57%, O 4.08%
Properties: mp 261-263°. Sol in water, ethanol. Practically insol in acetone, benzene, ether.
Melting point: mp 261-263°
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 5627-46-3››