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Mepivacaine CAS Registry Number: 96-88-8 甲哌卡因

CAS Name: N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide
Additional Names: 1-methyl-2',6'-pipecoloxylidide; dl-N-methylpipecolic acid 2,6-dimethylanilide; dl-N-methylhexahydropicolinic acid 2,6-dimethylanilide
Percent Composition: C 73.13%, H 9.00%, N 11.37%, O 6.49%

📌 参考资料/链接：
Literature References: Prepn: Ekenstam et al., Acta Chem. Scand. 11, 1183 (1957); US 2799679 (1957 to A. B. Bofors). Prepn of other salts: Rinderknecht, Helv. Chim. Acta 42, 1324 (1959); GB 826668 (1960 to Crookes Labs.). Resolution of isomers: Tullar, J. Med. Chem. 14, 891 (1971); Friberger, Aberg, Acta Pharm. Suec. 8, 361 (1971). Pharmacology: Helmy et al., J. Egypt. Med. Assoc. 50, 688 (1967). Metabolism: Reynolds, Br. J. Anaesth. 43, 33 (1971). Toxicity data: G. Aberg, Acta Pharmacol. Toxicol. 31, 273 (1972).

📄 详细内容

Properties: Crystals from ether, mp 150-151°.
Melting point: mp 150-151°
Derivative Type: Hydrochloride
CAS Registry Number: 1722-62-9
Trademarks: Carbocaina (Astra); Carbocaine hydrochloride (Winthrop); Chlorocain (Pharm. Mfg.); Meaverin (Woelm); Mepicaton (Pharmaton); Mepident (Parke-Davis); Mepivastesin (Espe); Optocain (Bayer); Scandicain (Bofors)
Percent Composition: C 63.70%, H 8.20%, N 9.91%, O 5.66%, Cl 12.54%
Properties: mp 262-264°. Sol in water. LD50 in mice, rats (mg/kg): 280, 500 s.c. (Aberg).
Melting point: mp 262-264°
Toxicity data: LD50 in mice, rats (mg/kg): 280, 500 s.c. (Aberg)
Derivative Type: (+)-Form
Additional Names: Dexivacaine
Therap-Cat: Anesthetic (local).
Therap-Cat-Vet: Anesthetic (local).
Keywords: Anesthetic (Local).
产品链接: 96-88-8››

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