Quinfamide CAS Registry Number: 62265-68-3 1-(二氯乙酰基)-6-(2-呋喃甲酰氧基)-1,2,3,4-四氢喹啉
CAS Name: 2-Furancarboxylic acid 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester
Additional Names: 2-furoic acid ester with 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinol; 1-(dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinolineTrademarks: Amenox (Sanofi Winthrop); Amenide (Sterling Winthrop)
Percent Composition: C 54.26%, H 3.70%, Cl 20.02%, N 3.95%, O 18.07%
📌 参考资料/链接：
Literature References: Prepn: D. M. Bailey, US 3997542 (1976 to Sterling); D. M. Bailey et al., J. Med. Chem. 22, 600 (1979). Amebicidal activity and toxicological evaluation: R. G. Slighter et al., Parasitology 81, 157 (1980). Distribution and metabolism in rats: J. F. Baker, Arch. Int. Pharmacodyn. 258, 29 (1982). HPLC determn in biological samples: J. M. Morales et al., J. Chromatogr. B 746, 133 (2000). Clinical evaluation in adults with chronic amebiasis: L. Guevara et al., Clin. Ther. 6, 43 (1983); in children: F. A. Rojas et al., ibid. 47.
📄 详细内容
Properties: Crystals from ethyl acetate, mp 150.5-151°.
Melting point: mp 150.5-151°
Therap-Cat: Antiamebic.
Keywords: Antiamebic.
产品链接: 62265-68-3››