网站主页>>>项目整合精选>>>项目整合精选>>>Vinbarbital Sodium CAS Registry Number: 125-44-0 5-乙基-5-(1-甲基-1-丁烯基)-2-钠氧基-4,6(1H,5H)-嘧啶二酮

Vinbarbital Sodium CAS Registry Number: 125-44-0 5-乙基-5-(1-甲基-1-丁烯基)-2-钠氧基-4,6(1H,5H)-嘧啶二酮

CAS Name: 5-Ethyl-5-(1-methyl-1-butenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt
Additional Names: 5-ethyl-5-(1-methyl-1-butenyl)barbituric acid sodium salt; sodium 5-ethyl-5-(1-methyl-1-butenyl)barbiturate
Trademarks: Delvinal Sodium (Merck Co.)
Percent Composition: C 53.65%, H 6.14%, N 11.38%, Na 9.34%, O 19.49%

📌 参考资料/链接：
Literature References: Prepn: Cope, Hancock, J. Am. Chem. Soc. 61, 776 (1939); Cope, US 2187703 (1940 to Sharp Dohme). Pharmacology and toxicity: J. P. Hendrix, J. Pharmacol. Exp. Ther. 68, 22 (1940).

📄 详细内容

Properties: Hygroscopic crystals, bitter taste. Slightly sol in ether and chloroform. A 1% aq soln is alkaline to phenolphthalein and has a pH between 8.5 and 9.5. Unbuffered aq solns are unstable. LD50 orally in rats: 130 mg/kg (Hendrix).
Toxicity data: LD50 orally in rats: 130 mg/kg (Hendrix)
Derivative Type: Free acid
Percent Composition: C 59.18%, H 6.77%, N 12.55%, O 21.50%
Properties: mp 161-163°.
Melting point: mp 161-163°
NOTE: This is a controlled substance (depressant):
21 CFR, 1308.13.
Therap-Cat: Sedative, hypnotic.
Therap-Cat-Vet: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 125-44-0››

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