网站主页>>>项目整合精选>>>项目整合精选>>>Propiverine CAS Registry Number: 60569-19-9 丙哌维林

Propiverine CAS Registry Number: 60569-19-9 丙哌维林

CAS Name: a-Phenyl-a-propoxybenzeneacetic acid 1-methyl-4-piperidinyl ester
Additional Names: a,a-diphenyl-a-propoxyacetic acid 1-methyl-4-piperidyl ester; 1-methyl-4-piperidyl diphenylpropoxyacetate
Percent Composition: C 75.17%, H 7.95%, N 3.81%, O 13.06%

📌 参考资料/链接：
Literature References: Prepn: C. Starke et al., DD 106643 (1974), C.A. 82, 155841s (1975). GC-MS determn in plasma and urine: T. Marunaka et al., J. Chromatogr. 420, 43 (1987). Pharmacology: A. Haruno, Arzneim.-Forsch. 42, 815, 1459 (1992). Acute toxicity: K. Yamashita et al., J. Toxicol. Sci. 14, Suppl. 2, 1 (1989), C.A. 112, 172060 (1990). Clinical pharmacokinetics: C. Müller et al., Eur. J. Drug Metab. Pharmacokinet. 18, 265 (1993). Clinical trial in urinary incontinence: D. Mazur et al., Urologe A33, 447 (1994).

📄 详细内容

Derivative Type: Hydrochloride
CAS Registry Number: 54556-98-8Trademarks: Detrunorm (Schering); Mictonorm (Apogepha); Mictonetten (Apogepha)
Percent Composition: C 68.39%, H 7.49%, N 3.47%, O 11.88%, Cl 8.78%
Properties: mp 216-218°. Sparingly sol in water and ethanol. LD50 in male, female mice, male, female rats (mg/kg): 36, 36, 22, 25 i.v.; 223, 283, 1632, 1411 s.c.; 410, 323, 1000, 1092 orally (Yamashita).
Melting point: mp 216-218°
Toxicity data: LD50 in male, female mice, male, female rats (mg/kg): 36, 36, 22, 25 i.v.; 223, 283, 1632, 1411 s.c.; 410, 323, 1000, 1092 orally (Yamashita)
Therap-Cat: In treatment of urinary incontinence.
Keywords: Antimuscarinic.
产品链接: 60569-19-9››

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