Properties: Yellow oil. Amine odor. bp0.1 138-142°, bp1.7 185-190°, bp20 193-205°. nD25 1.5759-1.5765. Miscible with water.
Boiling point: bp0.1 138-142°; bp1.7 185-190°; bp20 193-205°
Index of refraction: nD25 1.5759-1.5765
Derivative Type: Hydrochloride
CAS Registry Number: 154-69-8
Trademarks: Dehistin (EGYT); Azaron (Chefaro); Pyribenzamine (Novartis); PBZ (Novartis); Vetibenzamina (Novartis)
Percent Composition: C 65.85%, H 7.60%, N 14.40%, Cl 12.15%
Properties: Crystals from ethyl acetate + methanol, mp 192-193°. Bitter taste, produces temporary numbness of the tongue. uv max (water): 244, 305 (e 14470, 4780). One gram dissolves in 0.77 ml water, in 6 ml alcohol, in 6 ml chloroform, in about 350 ml acetone. Practically insol in benzene, ether, ethyl acetate. About neutral to litmus. pH of aq soln contg 25 mg/ml: 6.71; 50 mg/ml: 6.67; 100 mg/ml: 5.56. LD50 in mice (mg/kg): 47 i.p. (Walker).
Melting point: mp 192-193°
Absorption maximum: uv max (water): 244, 305 (e 14470, 4780)
Toxicity data: LD50 in mice (mg/kg): 47 i.p. (Walker)
Derivative Type: Citrate
CAS Registry Number: 6138-56-3
Percent Composition: C 59.05%, H 6.53%, N 9.39%, O 25.03%
Properties: Crystals, mp 106-110°. Less bitter than the hydrochloride. Freely sol in water, alcohol. Very slightly sol in ether. Practically insol in benzene, chloroform. 1% aq soln has a pH of 4.25.
Melting point: mp 106-110°
Therap-Cat: Antihistaminic.
Therap-Cat-Vet: Antihistaminic.
Keywords: Antihistaminic; Ethylenediamine Derivatives.
产品链接: 91-81-6››