Oxfendazole CAS Registry Number: 53716-50-0 奥芬达唑
CAS Name: [5-(Phenylsulfinyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester
Additional Names: methyl-5-(phenylsulfinyl)-2-benzimidazolecarbamate; 5-phenylsulfinyl-2-carbomethoxyaminobenzimidazoleTrademarks: Autoworm (Schering-Plough); Benzelmin (Fort Dodge); Synanthic (Fort Dodge); Systamex (Schering-Plough)
Percent Composition: C 57.13%, H 4.16%, N 13.32%, O 15.22%, S 10.17%
📌 参考资料/链接：
Literature References: Prepn: C. Beard et al., DE 2363351; eidem, US 3929821 (1974, 1975, both to Syntex); E. A. Averkin et al., J. Med. Chem. 18, 1164 (1975). Metabolism: J. P. Bell, R. V. Tomlinson, Fed. Proc. 35, 487 (1976). Radioimmunoassay: C. Nerenberg et al., J. Pharm. Sci. 67, 1553 (1978). Efficacy evaluations: J. L. Duncan, J. G. Reid, Vet. Rec. 103, 332 (1978); N. F. Baker et al., Am. J. Vet. Res. 39, 1258 (1978).
📄 详细内容
Properties: Crystals from chloroform-methanol, mp 253° (dec). LD50 in dogs, rats, mice: 1600, 6400, 6400 mg/kg (Averkin).
Melting point: mp 253° (dec)
Toxicity data: LD50 in dogs, rats, mice: 1600, 6400, 6400 mg/kg (Averkin)
Therap-Cat-Vet: Anthelmintic.
产品链接: 53716-50-0››