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Triamcinolone CAS Registry Number: 124-94-7 曲安西龙

CAS Name: (11b, 16a)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
Additional Names: D1-9a-fluoro-16a-hydroxyhydrocortisone; 9a-fluoro-16a-hydroxyprednisolone; D1-16a-hydroxy-9a-fluorohydrocortisone; 16a-hydroxy-9a-fluoroprednisoloneTrademarks: Aristocort (Lederle); Kenacort (BMS); Ledercort (tabl.) (Lederle); Omcilon (BMS); Tricortale (Bergamon); Volon (BMS)
Percent Composition: C 63.95%, H 6.90%, F 4.82%, O 24.34%

📌 参考资料/链接：
Literature References: Prepn: Bernstein et al., J. Am. Chem. Soc. 78, 5693 (1956); 81, 1689 (1959); Thoma et al., ibid. 79, 4818 (1957); Bernstein et al., Allen et al., US 2789118; US 3021347 (1957, 1962, both to Am. Cyanamid). Comprehensive description: K. Florey, Anal. Profiles Drug Subs. 1, 367-396, 423-442 (1972); D. H. Sieh, ibid. 11, 593-614, 651-661 (1982).

📄 详细内容

Properties: Crystals, mp 269-271°. mp also reported as 260-262.5°. [a]D25 +75° (acetone). uv max: 238 nm (e 15800).
Melting point: mp 269-271°; mp also reported as 260-262.5°
Optical Rotation: [a]D25 +75° (acetone)
Absorption maximum: uv max: 238 nm (e 15800)
Derivative Type: 16,21-Diacetate
CAS Registry Number: 67-78-7
CAS Name: (11b,16a)-16,21-Bis(acetyloxy)-9-fluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione
Additional Names: 16a,21-diacetoxy-9a-fluoro-11b,17a-dihydroxy-1,4-pregnadiene-3,20-dione
Trademarks: Cenocort (Central Pharm.); CINO-40 (Tutag); Tracilon (Savage)
Percent Composition: C 62.75%, H 6.53%, F 3.97%, O 26.75%
Properties: Solvated crystals, mp 186-188° (with effervescence, mp 235° after drying). [a]D25 +22° (chloroform). uv max: 239 nm (e 15200).
Melting point: Solvated crystals, mp 186-188° (with effervescence, mp 235° after drying)
Optical Rotation: [a]D25 +22° (chloroform)
Absorption maximum: uv max: 239 nm (e 15200)
Therap-Cat: Glucocorticoid.
Therap-Cat-Vet: Glucocorticoid.
Keywords: Glucocorticoid.
产品链接: 124-94-7››

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