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Secobarbital Sodium CAS Registry Number: 309-43-3 司可巴比妥钠

CAS Name: 5-(1-Methylbutyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione monosodium salt
Additional Names: sodium 5-allyl-5-(1-methylbutyl)barbiturate; 5-allyl-5-(1-methylbutyl)barbituric acid sodium salt; 5-allyl-5-(1-methylbutyl)malonylurea sodium salt; meballymal sodium; quinalbarbitone sodium
Trademarks: Barbosec (Rowell); Immenoctal (Houd?; Pramil (HÝsle); Quinalspan (Pharmax); Sedutain (Key); Seconal Sodium (Lilly); Seotalnatrium (Lilly)
Percent Composition: C 55.38%, H 6.58%, N 10.76%, Na 8.83%, O 18.44%

📌 参考资料/链接：
Literature References: Prepn: US 1954429 (1934). Comprehensive description: I. Comer, Anal. Profiles Drug Subs. 1, 343-365 (1972). Toxicity data: E. W. Schafer, Toxicol. Appl. Pharmacol. 21, 315 (1972).

📄 详细内容

Properties: White, hygroscopic powder. Bitter taste. Very sol in water. Sol in alc. Practically insol in ether. Aq solns are alkaline to litmus. The soly in elixirs is increased by the presence of methenamine. LD50 orally in rats: 125 mg/kg (Schafer).
Toxicity data: LD50 orally in rats: 125 mg/kg (Schafer)
Derivative Type: Free acid
Percent Composition: C 60.49%, H 7.61%, N 11.76%, O 20.14%
Properties: mp 100°.
Melting point: mp 100°
NOTE: This is a controlled substance (depressant):
21 CFR, 1308.12 and 1308.13.
Therap-Cat: Sedative; hypnotic.
Therap-Cat-Vet: Short-acting hypnotic; sedative. Pre-anesthetic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.
产品链接: 309-43-3››

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