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Chlorprothixene CAS Registry Number: 113-59-7 氯普噻吨

CAS Name: (Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-1-propanamine
Additional Names: (Z)-2-chloro-N,N-dimethylthioxanthene-D9,g-propylamine; cis-2-chloro-N,N-dimethyl-3-thioxanthen-9-ylidenepropylamine; a-2-chloro-10-(3-dimethylaminopropylidene)thiaxantheneTrademarks: Taractan (Roche); Tarasan (Roche); Truxal (Lundbeck); Truxaletten (Lundbeck)
Percent Composition: C 68.45%, H 5.74%, Cl 11.22%, N 4.43%, S 10.15%

📌 参考资料/链接：
Literature References: Prepn: GB 829763; E. L. Engelhardt, US 3046283 (1960, 1962 both to Merck Co.). Structure-activity study: G. E. Bonvicino et al., J. Org. Chem. 26, 2383 (1961). Comprehensive description: B. C. Rudy, B. Z. Senkowski, Anal. Profiles Drug Subs. 2, 63-84 (1973). HPLC determn in serum: M. Bagli et al., J. Chromatogr. B 657, 141 (1994). Clinical pharmacokinetics: idem et al., Arzneim.-Forsch. 46, 247 (1996).

📄 详细内容

Properties: Pale yellow crystals, mp 97-98°. Practically insol in water; sol in alcohol, ether, chloroform. Incompatible with acids, alkalies, phenobarbital, thiopental sodium, mepazine.
Melting point: mp 97-98°
Derivative Type: Hydrochloride
CAS Registry Number: 6469-93-8
Percent Composition: C 61.36%, H 5.44%, Cl 20.13%, N 3.98%, S 9.10%
Properties: Crystals, mp 221°. Freely sol in water at pH 6 to 6.5.
Melting point: mp 221°
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Thioxanthenes.
产品链接: 113-59-7››

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