Bisacodyl CAS Registry Number: 603-50-9 比沙可啶
CAS Name: 4,4'-(2-Pyridylmethylene)bisphenol diacetate
Additional Names: bis(p-acetoxyphenyl)-2-pyridylmethane; (4,4'-diacetoxydiphenyl)(2-pyridyl)methane; 2-(4,4'-diacetoxydiphenylmethyl)pyridine
Trademarks: Contalax (3M Pharma); Correctol (Schering-Plough); Dulcolan (Boehringer, Ing.); Dulcolax (Boehringer, Ing.); Durolax (Boehringer, Ing.); Ex-Lax Ultra (Novartis); Gentlax (Purdue Frederick); Laxadin (Teva); Perilax (Ferring); Pyrilax (Berlin-Chemie); Stadalax (Stada)
Percent Composition: C 73.12%, H 5.30%, N 3.88%, O 17.71%
📌 参考资料/链接：
Literature References: Prepn: GB 730243; A. Kottler, E. Seeger, US 2764590 (l955, 1956 both to Thomae). Pharmacology and toxicology: Schmidt, Arzneim.-Forsch. 3, 19 (1953). Comparison of efficacy and safety with other stimulant laxatives: A. Wald, J. Clin. Gastroenterol. 36, 386 (2003).
📄 详细内容
Properties: Tasteless crystals, mp 138°. Practically insol in water and alkaline solns. Sol in acids, alc, acetone, propylene glycol, and other organic solvents. LD50 orally in rats: 3 g/kg (Schmidt).
Melting point: mp 138°
Toxicity data: LD50 orally in rats: 3 g/kg (Schmidt)
Derivative Type: Complex with tannin
CAS Registry Number: 1336-29-4
Additional Names: Bisacodyl tannex
Trademarks: Clysodrast (Barnes-Hind)
Therap-Cat: Cathartic.
Keywords: Laxative/Cathartic.
产品链接: 603-50-9››