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Piperocaine CAS Registry Number: 136-82-3 哌罗卡因

CAS Name: 2-Methyl-1-piperidinepropanol benzoate
Additional Names: g-(2-methylpiperidyl)propyl benzoate; (2-methylpiperidino)propyl benzoate; 3-benzoxy-1-(2-methylpiperidino)propane; benzoyl-g-(2-methylpiperidino)propanol
Percent Composition: C 73.53%, H 8.87%, N 5.36%, O 12.24%

📌 参考资料/链接：
Literature References: Prepn of the hydrochloride: S. M. McElvain, US 1784903 (1930). Pharmacology: K. H. Beyer, A. R. Latven, J. Pharmacol. Exp. Ther. 106, 37 (1952). Structure activity study: P. P. Koelzer, K. H. Wehr, Arzneim.-Forsch. 8, 708 (1958).

📄 详细内容

Properties: LD50 i.v. in rabbits: 18 ±6 mg/kg (Beyer, Latven).
Toxicity data: LD50 i.v. in rabbits: 18 ±6 mg/kg (Beyer, Latven)
Derivative Type: Hydrochloride
CAS Registry Number: 533-28-8
Percent Composition: C 64.53%, H 8.12%, N 4.70%, O 10.74%, Cl 11.90%
Properties: Crystals from alc-ether, mp 167-169°. Stable in air. One gram dissolves in 1.5 ml water, 4.5 ml alcohol. Sol in alc, chloroform. Practically insol in ether, fixed oils. LD50 in mice (mg/20g): 9 s.c.; in rats (mg/kg): 129 i.p. (Koelzer).
Melting point: mp 167-169°. Stable in air
Toxicity data: LD50 in mice (mg/20g): 9 s.c.; in rats (mg/kg): 129 i.p. (Koelzer)
Therap-Cat: Anesthetic (local).
Therap-Cat-Vet: Anesthetic (local).
Keywords: Anesthetic (Local).
产品链接: 136-82-3››

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