Fluazacort CAS Registry Number: 19888-56-3 氟扎可特
CAS Name: (11b,16b)-21-(Acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione
Additional Names: 9-fluoro-11b,21-dihydroxy-2'-methyl-5'bH-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 21-acetateTrademarks: Azacortid (Lepetit)
Percent Composition: C 65.35%, H 6.58%, F 4.13%, N 3.05%, O 20.89%
📌 参考资料/链接：
Literature References: Prepn of the 21-hydroxy compound: G. Nathansohn et al., J. Med. Chem. 10, 799 (1967); of the 21-hydroxy and fluazacort: eidem, GB 1119082; eidem, US 3461119 (1968, 1969 to Lepetit); eidem, Steroids 13, 383 (1969). Pharmacological and physico-chemical properties: eidem, ibid. 365. Percutaneous absorption: J. D. Lewis et al., Arzneim.-Forsch. 25, 1646 (1975).
📄 详细内容
Properties: Crystals from ethanol, mp 252-255°. [a]D +54.8° (c = 0.5 in CHCl3). uv max (methanol): 238-240 nm (E1%1cm 330).
Melting point: mp 252-255°
Optical Rotation: [a]D +54.8° (c = 0.5 in CHCl3)
Absorption maximum: uv max (methanol): 238-240 nm (E1%1cm 330)
Therap-Cat: Anti-inflammatory.
Keywords: Glucocorticoid.
产品链接: 19888-56-3››