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Flufenamic Acid CAS Registry Number: 530-78-9 氟芬那酸

CAS Name: 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid
Additional Names: N-(a,a,a-trifluoro-m-tolyl)anthranilic acid; 3'-trifluoromethyldiphenylamine-2-carboxylic acidTrademarks: Achless (Tatsumi); Ansatin (Ono); Arlef (Parke-Davis); Fullsafe (Ohta); Meralen (HMR); Paraflu (Dainippon); Parlef (Parke-Davis); Ristogen (Kowa Yakuhin); Sastridex (Lindopharm); Surika (Thiemann); Tecramine
Percent Composition: C 59.79%, H 3.58%, F 20.27%, N 4.98%, O 11.38%

📌 参考资料/链接：
Literature References: Prepn from m-aminobenzotrifluoride and o-iodobenzoic acid: Wilkinson, Finar, J. Chem. Soc. 1948, 32. Pharmacology: Winder et al., Arthritis Rheum. 6, 36 (1963); 12, 472 (1969). Antiviral activity: Inglot, J. Gen. Virol. 4, 203 (1969). Toxicity data: Zoni et al., Farmaco Ed. Sci. 26, 191 (1971). Comprehensive description: E. Abignente, P. deCaprariis, Anal. Profiles Drug Subs. 11, 313-346 (1982).

📄 详细内容

Properties: Pale yellow needles from 50% alc, mp 125°. LD50 in mice: 715 mg/kg orally (Zoni).
Melting point: mp 125°
Toxicity data: LD50 in mice: 715 mg/kg orally (Zoni)
Derivative Type: Aluminum salt
CAS Registry Number: 61891-34-7
Additional Names: Aluminum flufenamate
Trademarks: Alfenamin; Opyrin (Taisho)
Percent Composition: C 58.14%, H 3.14%, Al 3.11%, F 19.71%, N 4.84%, O 11.06%
Derivative Type: Butyl ester
CAS Registry Number: 67330-25-0
Trademarks: Fenazol (Hokuriku Seiyaku); Combec (Tokyo Tanabe)
Percent Composition: C 64.09%, H 5.38%, F 16.90%, N 4.15%, O 9.49%
Therap-Cat: Anti-inflammatory; analgesic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Aminoarylcarboxylic Acid Derivatives.
产品链接: 530-78-9››

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