Derivative Type: L-Form
Properties: Crystals, dec 266°. [a]D25.3 +33.23° (c = 1.992 in 1% NaHCO3).
Optical Rotation: [a]D25.3 +33.23° (c = 1.992 in 1% NaHCO3)
Derivative Type: D-Form
Properties: Crystals from water, dec 266°. [a]D25.3 -31.54° (c = 2.01 in 1% NaHCO3).
Optical Rotation: [a]D25.3 -31.54° (c = 2.01 in 1% NaHCO3)
Derivative Type: DL-Form
Properties: Crystals, dec 259°. Forms a water-sol salt.
Use: The L- and DL-dihydroorotic acids are precursors to the biological pyrimidines, such as thymine, uracil, cytosine and hydroxymethylcytosine. When employed in large amounts D-dihydroorotic acid is an antimetabolite of L-dihydroorotic acid in pyrimidine utilization. It has also been found to inhibit the orotic acid utilization of those organisms which have a requirement for it in order to grow. In general it may be said to inhibit bacterial growth.
产品链接: 155-54-4››