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Plafibride CAS Registry Number: 63394-05-8 普拉贝脲

CAS Name: 2-(4-Chlorophenoxy)-2-methyl-N-[[(4-morpholinylmethyl)amino]carbonyl]propanamide
Additional Names: N-2-(p-chlorophenoxy)isobutyryl-N'-morpholinomethylureaTrademarks: Idonor (Roger); Perifunal (Aristegui)
Percent Composition: C 54.01%, H 6.23%, Cl 9.96%, N 11.81%, O 17.99%

📌 参考资料/链接：
Literature References: Analog of clofibrate, q.v. Prepn: J. Iniesta-Pons, DE 2716374 (1977 to Investigacion Tecnica y Aplicada), C.A. 88, 37810g (1978). Toxicity data: J. Zapatero, L. Brugeghini, Arch. Farmacol. Toxicol. 4, 137 (1978). Series of articles on antiplatelet aggregation activity, hypolipemic activity, pharmacology, and toxicology: ibid., 132-142.

📄 详细内容

Properties: Crystals, mp 100-102°. Sol in acetone. Slightly sol in alcohol. Practically insol in water, petr ether. LD50 in mice, rats, guinea pigs (mg/kg): 3569, 4000, 2168 orally (Zapatero, Brugeghini).
Melting point: mp 100-102°
Toxicity data: LD50 in mice, rats, guinea pigs (mg/kg): 3569, 4000, 2168 orally (Zapatero, Brugeghini)
Therap-Cat: Antithrombotic.
Keywords: Antithrombotic.
产品链接: 63394-05-8››

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