Properties: Crystals from ether, mp 208-209° (not 92-93° as first given by McCawley). [a]D25 -155.3° (c = 3 in methanol). Sparingly sol in water, ether. Sol in alc, acetone, chloroform, dil alkalies. uv max (in acid): 285 nm; (in alkali): 298 nm.
Melting point: mp 208-209° (not 92-93° as first given by McCawley)
Optical Rotation: [a]D25 -155.3° (c = 3 in methanol)
Absorption maximum: uv max (in acid): 285 nm; (in alkali): 298 nm
Derivative Type: Hydrobromide
CAS Registry Number: 1041-90-3
Trademarks: Lethidrone (Burroughs Wellcome); Norfin (Lusofarmaco)
Percent Composition: C 58.17%, H 5.65%, N 3.57%, O 12.24%, Br 20.37%
Properties: Crystals from alc, dec 258-259°. Sol in water.
Derivative Type: Hydrochloride
CAS Registry Number: 57-29-4
Trademarks: Nalline (Merck Co.)
Percent Composition: C 65.61%, H 6.37%, N 4.03%, O 13.80%, Cl 10.19%
Properties: Crystals from alc, mp 260-263°. Sol in water. Moderately sol in alc. uv max (water): 285 nm. IR and polarographic data: Seagers et al., J. Am. Pharm. Assoc. Sci. Ed.
41, 640 (1952). pH of 0.5% aq soln: 5.0. LD50 s.c. in rats: 1460 mg/kg (Goldenthal).
Melting point: mp 260-263°
Absorption maximum: uv max (water): 285 nm
Toxicity data: LD50 s.c. in rats: 1460 mg/kg (Goldenthal)
NOTE: This is a controlled substance:
21 CFR, 1308.13.
Therap-Cat: Narcotic antagonist.
Therap-Cat-Vet: Narcotic antagonist.
Keywords: Narcotic Antagonist.
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