Aminopterin CAS Registry Number: 54-62-6 氨基蝶呤
CAS Name: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
Additional Names: 4-aminofolic acid; 4-aminopteroylglutamic acid; 4-amino-PGA
Percent Composition: C 51.82%, H 4.58%, N 25.44%, O 18.16%
📌 参考资料/链接：
Literature References: Prepd from 2,4,5,6-tetraminopyrimidine sulfate, 2,3-dibromopropionaldehyde and p-aminobenzoylglutamic acid: Seeger et al., J. Am. Chem. Soc. 69, 2567 (1947); from 6-(bromomethyl)-2,4-diaminopteridine HBr: Piper, Montgomery, J. Heterocycl. Chem. 11, 279 (1974). Purification: Loo, J. Med. Chem. 8, 139 (1965). Inhibition of dihydrofolate reductase: J. S. Erickson et al., J. Biol. Chem. 247, 5661 (1972). Use as rodenticide: US 2575168 (1951 to Am. Cyanamid).
📄 详细内容
Derivative Type: Dihydrate
Properties: Clusters of yellow needles. uv max of the 0.75 hydrate (0.1N NaOH): 261, 282, 373 (log e 4.41, 4.39, 3.91).
Absorption maximum: uv max of the 0.75 hydrate (0.1N NaOH): 261, 282, 373 (log e 4.41, 4.39, 3.91)
Use: Rodenticide.
产品链接: 54-62-6››