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Carbuterol CAS Registry Number: 34866-47-2 卡布特罗

CAS Name: [5-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]urea
Additional Names: a-(t-butylaminomethyl)-4-hydroxy-3-ureidobenzyl alcohol
Percent Composition: C 58.41%, H 7.92%, N 15.72%, O 17.96%

📌 参考资料/链接：
Literature References: A b-adrenergic agonist related to isoproterenol, q.v., with selectivity for airway smooth muscle receptors. Prepn: C. Kaiser, S. T. Ross, DE 2106620; eidem, US 3763232 (1971, 1973 both to SKF); C. Kaiser et al., J. Med. Chem. 17, 49 (1974). Pharmacology, mechanism of action, toxicity study: J. R. Wardell et al., J. Pharmacol. Exp. Ther. 189, 167 (1974). Analysis in aq soln: L. J. Ravin et al., J. Pharm. Sci. 67, 1523 (1978). Clinical study: T. D. James, H. A. Lyons, J. Am. Med. Assoc. 241, 704 (1979).

📄 详细内容

Properties: Crystals, mp 174-176°. LD50 in mice (mg/kg): 32.8 i.v.; 3134.6 orally; in rats: 77.2 i.v. (Wardell).
Melting point: mp 174-176°
Toxicity data: LD50 in mice (mg/kg): 32.8 i.v.; 3134.6 orally; in rats: 77.2 i.v. (Wardell)
Derivative Type: Hydrochloride
CAS Registry Number: 34866-46-1Trademarks: Bronsecur (SK F); Pirem (Gecke)
Percent Composition: C 51.40%, H 7.30%, N 13.83%, O 15.80%, Cl 11.67%
Properties: Crystals from ethanol/ether, mp 205-207° (dec).
Melting point: mp 205-207° (dec)
Therap-Cat: Bronchodilator.
Keywords: ?Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives.
产品链接: 34866-47-2››

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