Adlumidine CAS Registry Number: 550-49-2 山缘草定碱
CAS Name: (6S)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one
Percent Composition: C 65.39%, H 4.66%, N 3.81%, O 26.13%
📌 参考资料/链接：
Literature References: An alkaloid present in the d-form in the entire plant of Adlumia fungosa (Ait.) Greene (A. cirrhosa Raf.), Corydalis thalictrifolia Franch. and C. incisa (Thumb.) Pers., Fumariaceae. Schlotterbeck, Watkins, J. Am. Chem. Soc. 25, 596 (1903); R. H. F. Manske, Can. J. Res. 21B, 111 (1943). l-Adlumidine was isolated from Corydalis sempervirens (L.) Pers., C. scouleri Hook., and C. crystallina Engelm., Fumariaceae: R. H. F. Manske, ibid. 8, 407 (1932); 14B, 347 (1936); 17B, 57 (1939). Structure: idem, J. Am. Chem. Soc. 72, 3207 (1950). Stereochemistry: Blaha et al., Collect. Czech. Chem. Commun. 29, 2328 (1964); Snatzke et al., Tetrahedron 25, 5059 (1969). Review: Stanek, Manske in The Alkaloids vol. IV, R. H. F. Manske, H. L. Holmes, Eds. (Academic Press, New York, 1954) pp 167-198. Stereoisomer of bicuculline, q.v.
📄 详细内容
Properties: Rhombic plates from chloroform + methanol, mp 236-237°. [a]D25 +116.2° (c = 22 in chloroform). pKa 4.27. Practically insol in water. Very sparingly sol in alcohol, ether, hexane.
Melting point: mp 236-237°
pKa: pKa 4.27
Optical Rotation: [a]D25 +116.2° (c = 22 in chloroform)
Derivative Type: l-Adlumidine
CAS Registry Number: 485-50-7
Additional Names: Capnoidine
Properties: Stout prisms from chloroform + methanol, mp 238°. [a]D22 -113.2° (in chloroform). pKa 4.24. Practically insol in water. Sparingly sol in methanol; sol in chloroform.
Melting point: mp 238°
pKa: pKa 4.24
Optical Rotation: [a]D22 -113.2° (in chloroform)
产品链接: 550-49-2››