Glucosulfone Sodium CAS Registry Number: 554-18-7 葡胺苯砜
CAS Name: 1,1'-[Sulfonylbis(4,1-phenyleneimino)]bis[1-deoxy-1-sulfo-D-glucitol] disodium salt
Additional Names: p,p'-sulfonyldianiline N,N'-diglucoside disodium disulfonate; p,p'-sulfonyldianiline-N,N'-di-D-glucose sodium bisulfite compd; p,p'-diaminodiphenylsulfone-N,N'-di(dextrose sodium sulfonate); disodium p,p'-diaminodiphenylsulfone-N,N'-diglucose sulfonateTrademarks: Protomin; Promin (Parke-Davis); Promanide
Percent Composition: C 36.92%, H 4.39%, N 3.59%, Na 5.89%, O 36.89%, S 12.32%
📌 参考资料/链接：
Literature References: Prepd by refluxing a mixture of 4,4¢-diaminodiphenylsulfone, glucose, sodium bisulfite, and 80% ethanol: CH 234108 (1944 to B. Siegfried), C.A. 43, 4297a (1949); B. C. Jain et al., Sci. Cult. 11, 568 (1946). Structure activity study: W. Logemann, G. P. Miori, Arzneim.-Forsch. 5, 213 (1955). Clinical evaluation in ocular leprosy: A. Bouzas, Arch. Ophthalmol. 31, 629 (1971).
📄 详细内容
Properties: White, amorphous powder. Soluble in water; slightly sol in ethanol. Insol in ether, benzene, methanol, ethyl acetate, pyridine. Aq solns may be sterilized by autoclaving. LD50 in rats (g/kg): 3-4 orally, 3-3.5 i.v. (Logemann, Miori).
Toxicity data: LD50 in rats (g/kg): 3-4 orally, 3-3.5 i.v. (Logemann, Miori)
Therap-Cat: Antibacterial (leprostatic).
Keywords: Antibacterial (Synthetic); Sulfones; Antibacterial (Leprostatic).
产品链接: 554-18-7››