网站主页>>>项目整合精选>>>项目整合精选>>>Sulfapyrazine CAS Registry Number: 116-44-9 4-氨基-N-(吡嗪-2-基)苯磺酰胺

Sulfapyrazine CAS Registry Number: 116-44-9 4-氨基-N-(吡嗪-2-基)苯磺酰胺


CAS Name: 4-Amino-N-(pyrazinyl)benzenesulfonamide
Additional Names: N1-2-pyrazinylsulfanilamide; 2-sulfanilamidopyrazine
Percent Composition: C 47.99%, H 4.03%, N 22.39%, O 12.79%, S 12.81%
📌 参考资料/链接:
Literature References: Prepd by reacting acetylsulfanilyl chloride with 2-aminopyrazine in pyridine, followed by hydrolysis and neutralization: Ellingson, US 2420703 (1947). Biological properties: Ghione et al., Chemotherapia 6, 344 (1962).

📄 详细内容


Properties: Crystals, dec 250-254°. Very slightly sol in alc; slightly sol in acetone. Sol in aq solns of sodium, potassium, and barium hydroxides, in ammonia water, and in dil and concd mineral acid solns. Practically insol in water (5 mg/100 ml at 25°, and 5.2 mg/100 ml at 37°).
Derivative Type: Sodium salt monohydrate
Percent Composition: C 41.38%, H 3.82%, N 19.30%, Na 7.92%, O 16.54%, S 11.05%
Properties: Bitter powder. Freely soluble in water (1 g/3.33 ml at 25°). Alkaline to litmus. pH of 10% aq soln 9.1. Very sol in acetone, slightly sol in alc. Insol in ether, chloroform. Aq solns of sulfapyrazine sodium may absorb carbon dioxide which causes precipitation of sulfapyrazine.
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial.
Keywords: Antibacterial (Synthetic); Sulfonamides.
产品链接: 116-44-9››