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Sulfasomizole CAS Registry Number: 632-00-8 磺胺异噻唑

CAS Name: 4-Amino-N-(3-methyl-5-isothiazolyl)benzenesulfonamide
Additional Names: 3-methyl-5-sulfanilamidoisothiazole; 5-p-aminobenzenesulfonamido-3-methylisothiazole; 5-sulfanilamido-3-methylisothiazole; N1-(3-methylisothiazol-5-yl)sulfanilamide; sulphasomizole
Trademarks: Bidizole; Amidozol
Percent Composition: C 44.59%, H 4.12%, N 15.60%, O 11.88%, S 23.81%

📌 参考资料/链接：
Literature References: Preparation from N-acetylsulfanilyl chloride and 5-amino-3-methylisothiazole in pyridine followed by deacetylation in 2N NaOH: Adams, Slack, J. Chem. Soc. 1959, 3070; Adams et al., Nature 186, 221 (1960); GB 835753 (1960 to May Baker).

📄 详细内容

Properties: Cream-colored needles from H2O, mp 192-192.5°. Soly in H2O at pH 6.0: 248 mg/100 ml; at pH 7.0: 2.26 g/100 ml.
Melting point: mp 192-192.5°
Derivative Type: Sodium salt monohydrate
Percent Composition: C 38.83%, H 3.91%, N 13.58%, Na 7.43%, O 15.52%, S 20.73%
Properties: Crystals, when anhydr dec 345°. Freely sol in water. Aq solns of almost neutral pH contg more than 50% w/v of the sodium salt can be made.
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Sulfonamides.
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 632-00-8››

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