Properties: Gray to brown powder, decomp 215-220°. Has 2-3% absorbed or combined moisture. Stable to light, air and temps up to 50°. Practically insol in water. Sol in alcohol (about 28 mg/ml), in methanol and in propylene glycol. One part of a 2% alcoholic soln contg 10% formaldehyde soln U.S.P. dissolves in 49 parts of water without cloudiness. Tyrothricin should not be dissolved in ether or acetone as only the gramicidin component is soluble. Soly in mg/ml at about 28°: water 2.1; isopropanol 5.6; benzene 0.30; isooctane 0.042; carbon tetrachloride 0.455; ethyl acetate 2.65; acetone 6.8; ether 3.25; dioxane 11.1; chloroform 1.6. Aqueous suspensions may be attacked by microorganisms. Solutions and emulsions should not be sterilized by heat. Incompatible with alkalies and strong acids. Tyrothricin gives a positive biuret and Hopkins-Cole test. LD50 in mice (mg/kg): 1500 s.c.; 100 i.p.; 3000 orally (Sous).
Toxicity data: LD50 in mice (mg/kg): 1500 s.c.; 100 i.p.; 3000 orally (Sous)
Therap-Cat: Topical antibacterial.
Therap-Cat-Vet: Topical antibacterial.
Keywords: Antibacterial (Antibiotics); Polypeptides.
产品链接: 1404-88-2››