Derivative Type: DL-Form
Properties: Prisms from ether, mp 99-100°. Poisonous! Hygroscopic, but only slightly sol in water; sol in alcohol, benzene, chloroform, ether, acetone, dil acids.
Melting point: mp 99-100°
Derivative Type: DL-Hydrobromide
CAS Registry Number: 51-56-9
Trademarks: Homatrisol (Cooper); Bufopto Homatrocel (Softcon)
Percent Composition: C 53.94%, H 6.22%, N 3.93%, O 13.47%, Br 22.43%
Properties: Orthorhombic, bipyramidal prisms from water, mp ~212° (partial decompn). Poisonous! One gram dissolves in 6 ml water, 40 ml alcohol (12 ml at 60°), 420 ml chloroform. Insol in ether. pH (1% aq soln): 5.4.
Melting point: mp ~212° (partial decompn)
Derivative Type: DL-Hydrochloride
Percent Composition: C 61.63%, H 7.11%, N 4.49%, O 15.39%, Cl 11.37%
Properties: Prisms from water, mp 217-220° (dec). Poisonous! Freely sol in water, alcohol. pH (1% aq soln): 5.4.
Melting point: mp 217-220° (dec)
Derivative Type: DL-Methylbromide
CAS Registry Number: 80-49-9
Trademarks: Arkitropin; Homapin (Mission Pharmacal); Malcotran (Fisons); Mesopin (Endo); Novatrin (Ayerst); Novatropine; Sethyl
Percent Composition: C 55.14%, H 6.53%, N 3.78%, O 12.96%, Br 21.58%
Properties: Minute needles from alc + ether, mp 191-192° (slight dec). Poisonous! Freely sol in water, dil alc; slightly sol in abs alc. Insol in ether. pH (1% aq soln) 5.9; pH (10% aq soln) 4.5. LD50 in mice (mg/kg): 1400 orally, 60 i.p. (Cahen, Tvede).
Melting point: mp 191-192° (slight dec)
Toxicity data: LD50 in mice (mg/kg): 1400 orally, 60 i.p. (Cahen, Tvede)
Therap-Cat: Mydriatic.
Keywords: Antimuscarinic; Mydriatic.
产品链接: 87-00-3››