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Felbinac CAS Registry Number: 5728-52-9 联苯乙酸

CAS Name: (1,1'-Biphenyl)-4-acetic acid
Additional Names: 4-biphenylacetic acid; 4-carboxymethylbiphenyl; BPAATrademarks: Napageln (Lederle); Traxam (Lederle)
Percent Composition: C 79.23%, H 5.70%, O 15.08%

📌 参考资料/链接：
Literature References: One of the metabolites of fenbufen, q.v. Prepn: E. Schwenk, D. Papa, J. Org. Chem. 11, 798 (1946). Improved prepn: G. R. Malone, A. I. Meyers, ibid. 39, 618 (1974). Pharmacology: A. E. Sloboda, A. C. Osterberg, Inflammation 1, 415 (1976). Mode of action study in ocular inflammation: E. L. Tolman et al., Invest. Ophthalmol. 15, 1005 (1976). HPLC determn in serum: J. S. Fleitman et al., J. Chromatogr. 228, 372 (1982).

📄 详细内容

Properties: White needles from ethyl ether, mp 164-165°. LD50 orally in rats: 164 mg/kg (Sloboda, Osterberg).
Melting point: mp 164-165°
Toxicity data: LD50 orally in rats: 164 mg/kg (Sloboda, Osterberg)
Derivative Type: Ethyl ester
CAS Registry Number: 14062-23-8Trademarks: Daitec (Lederle)
Percent Composition: C 79.97%, H 6.71%, O 13.32%
Therap-Cat: Anti-inflammatory, analgesic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Arylacetic Acid Derivatives.
产品链接: 5728-52-9››

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