网站主页>>>项目整合精选>>>项目整合精选>>>Actiphenol CAS Registry Number: 526-02-3 4-[2-(2-羟基-3,5-二甲基苯基)-2-氧代乙基]哌啶-2,6-二酮

Actiphenol CAS Registry Number: 526-02-3 4-[2-(2-羟基-3,5-二甲基苯基)-2-氧代乙基]哌啶-2,6-二酮


CAS Name: 4-[2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl]-2,6-piperidinedione
Additional Names: 3-(2-hydroxy-3,5-dimethylphenacyl)glutarimide; b-(3,5-dimethyl-2-hydroxybenzoylmethyl)glutarimidePercent Composition: C 65.44%, H 6.22%, N 5.09%, O 23.25%
📌 参考资料/链接:
Literature References: Metabolic product found in culture filtrates of cycloheximide-producing actinomycetes (Streptomyces albulus): Highet, Prelog, Helv. Chim. Acta 42, 1523 (1959); Rao, J. Org. Chem. 25, 661 (1960). Synthesis: Johnson, ibid. 27, 3658 (1962). May be prepd from cycloheximide: Highet, Prelog, loc. cit. Structure-activity studies: Ennis, Biochem. Pharmacol. 17, 1197 (1968).

📄 详细内容


Properties: Fluffy needles from methylene chloride + methanol. mp 200-202°. Pure crystals are white or colorless. uv max: 262, 345 nm (e 10870, 4550). Exhibits bright yellow fluorescence under u.v. Soluble in aqueous NaOH (forming bright yellow solns), in anhydr alcohol, tetrahydrofuran. Insol in aq solns of sodium bicarbonate.
Melting point: mp 200-202°
Absorption maximum: uv max: 262, 345 nm (e 10870, 4550)
Derivative Type: Acetate
Percent Composition: C 64.34%, H 6.03%, N 4.41%, O 25.21%
Properties: Crystals from methylene chloride + ether, mp 155.5°.
Melting point: mp 155.5°
产品链接: 526-02-3››