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Lodoxamide CAS Registry Number: 53882-12-5 诺朵腊酸

CAS Name: 2,2'-[(2-Chloro-5-cyano-1,3-phenylene)diimino]bis(2-oxoacetic acid)
Additional Names: N,N'-(2-chloro-5-cyano-m-phenylene)dioxamic acid
Percent Composition: C 42.40%, H 1.94%, Cl 11.38%, N 13.48%, O 30.80%

📌 参考资料/链接：
Literature References: Mast cell stabilizer. Prepn: C. M. Hall, J. B. Wright, DE 2362409; eidem, US 3993679 (1974, 1976 both to Upjohn); J. B. Wright et al., J. Med. Chem. 21, 930 (1978). HPLC determn in human plasma: I. L. Honigberg et al., J. Chromatogr. 276, 213 (1983). Mechanism of action study: M. K. Church, J. Hiroi, Br. J. Pharmacol. 90, 421 (1987). Clinical evaluation in asthma: R. L. Case et al., J. Am. Med. Assoc. 247, 661 (1982); in allergic eye disease: G. T. Fahy et al., Eur. J. Ophthalmol. 2, 144 (1992).

📄 详细内容

Properties: mp 212° (dec). uv max (0.1N NaOH) 239.5 (e 23800).
Melting point: mp 212° (dec)
Absorption maximum: uv max (0.1N NaOH) 239.5 (e 23800)
Derivative Type: Diethyl ester
CAS Registry Number: 53882-13-6
Additional Names: Diethyl N,N¢-(2-chloro-5-cyano-m-phenylene)dioxamate; lodoxamide ethylPercent Composition: C 48.99%, H 3.84%, Cl 9.64%, N 11.43%, O 26.10%
Properties: Crystals from ethanol, mp 177-179°.
Melting point: mp 177-179°
Derivative Type: Tromethamine salt
CAS Registry Number: 63610-09-3
Additional Names: Lodoxamide tromethamine; lodoxamide trometamolTrademarks: Alomide (Alcon)
Percent Composition: C 41.20%, H 5.10%, Cl 6.40%, N 12.64%, O 34.66%
Therap-Cat: Antiallergic; topically in allergic conjunctivitis.
Keywords: Antiallergic.
产品链接: 53882-12-5››

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