Streptomycin B CAS Registry Number: 128-45-0 D-链吡他明,O-b-D-甘诺吡嗪-(1-4)-氧-脱氧-2-(甲基氨基)-a-L-葡萄吡吡烷基-(1-2)-O-5-脱氧-3-C-甲酰-a-L-lyxo呋喃osyl-(1-4)-N1,N3-双(氨基亚氨基甲基)-
Additional Names: Mannosidostreptomycin; mannosylstreptomycin
Percent Composition: C 43.60%, H 6.64%, N 13.18%, O 36.57%
📌 参考资料/链接：
Literature References: Isoln from streptomycin concentrates: Fried, Titus, J. Biol. Chem. 168, 391 (1947); 174, 57 (1948); Fried, Stavely, J. Am. Chem. Soc. 69, 1549 (1947); Fried, Titus, ibid. 70, 3615 (1948); O'Keeffe et al., ibid. 71, 2452 (1949); see also Langlykke, Perlman, US 2493489 (1950 to Squibb). Structure: Fried, Stavely, 113th Meeting Am. Chem. Soc., Chicago, Ill. (April 20, 1948) Abstracts of Papers p 25C; Peck et al., J. Am. Chem. Soc. 70, 3968 (1948); Stavely, Fried, ibid. 71, 135 (1949); 74, 5461 (1952).
📄 详细内容
Properties: On catalytic hydrogenation absorbs approx one mole of hydrogen and forms dihydrostreptomycin B. Yields maltol on alkaline hydrolysis. When treated with dil acids liberates streptidine (or an isomer of it) isolated as the sulfate monohydrate, C8H18N6O4.H2SO4.H2O.
Derivative Type: Trihydrochloride monohydrate
Percent Composition: C 37.23%, H 6.25%, N 11.26%, O 33.06%, Cl 12.21%
Properties: White, amorphous powder; mp 190-200° (corr, decompn) after drying in vacuo at 100°. [a]D25 -47° (c = 1.35 in water). Appears to have about one-fourth of the antibiotic activity of streptomycin trihydrochloride.
Melting point: mp 190-200° (corr, decompn) after drying in vacuo at 100°
Optical Rotation: [a]D25 -47° (c = 1.35 in water)
Status: This monograph has been retired and is no longer subject to revision or update.
产品链接: 128-45-0››