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Pteropterin CAS Registry Number: 89-38-3

CAS Name: N-[N-[N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-g-glutamyl]-L-glutamyl]-L-glutamic acid
Additional Names: N-[N-(N-pteroyl-g-glutamyl)-g-glutamyl]glutamic acid; fermentation L. casei Factor; pterolyl-g-glutamyl-g-glutamylglutamic acid; pteroyldi-g-glutamylglutamic acid; pteroyltriglutamic acid; PTGA
Trademarks: Teropterin
Percent Composition: C 49.78%, H 4.75%, N 18.02%, O 27.44%

📌 参考资料/链接：
Literature References: Isoln from aerobic culture of Corynebacterium: Hutchings et al., J. Am. Chem. Soc. 70, 1 (1948). Identification, structure and synthesis: Boothe et al., ibid. 1099; ibid. 71, 2304 (1949). Prepn: Cosulich, US 2563707 (1951 to Am. Cyanamid).

📄 详细内容

Properties: Forms a crystalline barium salt.
Derivative Type: Monohydrate
Properties: Crystals from water adjusted to pH 2.8 with HCl and contg some NaCl. Has the general properties of a polypeptide. Absorption spectrum, Hutchings, loc. cit. Soly in water at 5°: 0.10 mg/ml; at 80°: 3.00 mg/ml. Sol in NaOH solns.
Derivative Type: Methyl ester
Properties: Crystals from methanol contg NaCl. Soly in water at 5°: 0.12 mg/ml; at 80°: 1.00 mg/ml; in methanol at -5°: 0.30 mg/ml; at 60°: 5.00 mg/ml.
Therap-Cat: Formerly as antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Folic Acid Analogs/Antagonists.
产品链接: 89-38-3››

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