Mivazerol CAS Registry Number: 125472-02-8 米伐折醇
CAS Name: 2-Hydroxy-3-(1H-imidazol-4-ylmethyl)benzamide
Additional Names: a-imidazol-4-yl-2,3-cresotamide
Percent Composition: C 60.82%, H 5.10%, N 19.34%, O 14.73%
📌 参考资料/链接:
Literature References: a2-Adrenergic agonist. Prepn: E. Cossement et al., EP 341231; eidem, US 4923865 (1989, 1990 both to UCB); idem et al., J. Pharm. Belg. 49, 206 (1994). Specificity for a2 adrenoceptors and binding studies: M. Noyer et al., Neurochem. Int. 24, 221 (1994). Clinical trial to improve perioperative hemodynamic stability: D. T. Mangano et al., Anesthesiology 86, 346 (1997). Mode of action study: M. Guyaux et al., Acta Anaesthesiol. Scand. 42, 238 (1998).
📄 详细内容
Properties: mp 197.6°.
Melting point: mp 197.6°
Derivative Type: Hydrochloride
CAS Registry Number: 127170-73-4Percent Composition: C 52.08%, H 4.77%, N 16.56%, O 12.61%, Cl 13.98%
Properties: mp 287.8°. LD50 i.p. in mice: 760 mg/kg (Cossement).
Melting point: mp 287.8°
Toxicity data: LD50 i.p. in mice: 760 mg/kg (Cossement).
Therap-Cat: To reduce cardiac complications of surgery.
Keywords: a-Adrenergic Agonist.
产品链接: 125472-02-8››