Properties: White or yellowish white prisms, mp 182-184°. Acidic, slightly saline taste. uv max (water, 0.1M HCl, 0.1M HCl, 0.1M NaOH): 258, 217, 270, 256 (am 17700, 18900, 8900, 17300). Soluble in 150 parts water at 20°, in 15 parts alcohol, in 7 parts acetone. Sol in mineral acids and soln of alkali hydroxides and carbonates. Slightly sol in ether; very slightly sol in chloroform. An aq soln is acid to litmus. LD50 orally in dogs: 8000 mg/kg (Fisher).
Melting point: mp 182-184°
Absorption maximum: uv max (water, 0.1M HCl, 0.1M HCl, 0.1M NaOH): 258, 217, 270, 256 (am 17700, 18900, 8900, 17300)
Toxicity data: LD50 orally in dogs: 8000 mg/kg (Fisher)
Derivative Type: Sodium salt
CAS Registry Number: 127-56-0; 6209-17-2 (monohydrate)
Additional Names: Soluble sulfacetamide
Trademarks: Ak-Sulf (Akorn); Albucid (Ankerpharm); Antébor (Biologiques); Beocid-Puroptal (Metochem); Bleph-10 (Allergan); Cetamide (Alcon); Prontamid (SIT); Sebizon (Schering); Sodium Sulamyd (Schering); Sulf-10 (Novartis); Sulten-10 (Bausch Lomb)
Percent Composition: C 40.68%, H 3.84%, N 11.86%, Na 9.73%, O 20.32%, S 13.57%
Properties: Minute prisms from dil alcohol, mp 257°. Occurs as the monohydrate; white, odorless, crystalline powder with slightly bitter taste. uv max (pH 7.0 phosphate buffer, 0.1M HCl, aq. acid, 0.1M NaOH, aq alkali): 255, 271, 271, 256, 256 (A1cm1% 660-720, 207, 260, 626, 750). Sol in 1.5 parts water. Slightly sol in 96% ethanol; sparingly sol in acetone. Practically insol in ether and chloroform. pKa1 (amino group): 1.8; pKa2 (sulfonamide group at 25°): 5.4.
Melting point: mp 257°
pKa: pKa1 (amino group): 1.8; pKa2 (sulfonamide group at 25°): 5.4
Absorption maximum: uv max (pH 7.0 phosphate buffer, 0.1M HCl, aq. acid, 0.1M NaOH, aq alkali): 255, 271, 271, 256, 256 (A1cm1% 660-720, 207, 260, 626, 750)
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial.
Keywords: Antibacterial (Synthetic); Sulfonamides.
产品链接: 144-80-9››