Rupatadine CAS Registry Number: 158876-82-5 芦帕他定

📌 参考资料/链接：
Literature References: Dual antagonist of histamine H1 and platelet-activating factor receptors. Prepn: E. Carceller et al., ES 2042421; eidem, US 5407941 (1993, 1995 both to Uriach); eidem, J. Med. Chem. 37, 2697 (1994). Mechanism of action: M. Merlos et al., J. Pharmacol. Exp. Ther. 280, 114 (1997). Clinical trial in seasonal allergic rhinitis: F. Saint-Martin et al., J. Invest. Allergol. Clin. Immunol. 14, 34 (2004); and comparison with ebastine: E. M. Guadaño et al., Allergy 59, 766 (2004). Review of pharmacology and clinical development: N. Y. Van Den Anker-Rakhmanina, Curr. Opin. Anti-Inflam. Immunomod. Invest. Drugs 2, 127-132 (2000).