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Lisuride CAS Registry Number: 18016-80-3 稠环乙脲

CAS Name: N'-[(8a)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethylurea
Additional Names: 9-(3,3-diethylureido)-4,6,6a,7,8,9-hexahydro-7-methylindolo[4,3-f,g]quinoline; 1,1-diethyl-3-(D-6-methylisoergolen-8-yl)urea; N-(D-6-methyl-8-isoergolenyl)-N,N-diethylurea; methylergol carbamide; lysuride
Percent Composition: C 70.97%, H 7.74%, N 16.55%, O 4.73%

📌 参考资料/链接：
Literature References: Dopamine D2-receptor agonist. Prepn: V. Zikan, M. Semonsky, Collect. Czech. Chem. Commun. 25, 1922 (1960); eidem, Pharmazie 23, 147 (1968). Pharmacology and toxicity: Z. Votava, I. Lamplova, Physiol. Bohemoslov. 12, 37 (1963), C.A. 59, 9221d (1963).

📄 详细内容

Properties: Crystals from benzene, mp 186°. [a]D20 +313° (c = 0.60 in pyridine).
Melting point: mp 186°
Optical Rotation: [a]D20 +313° (c = 0.60 in pyridine)
Derivative Type: Maleate
CAS Registry Number: 19875-60-6
Trademarks: Apodel (Meiji); Cuvalit (Schering AG); Dopergin (Schering AG); Eunal (Schering); Lysenyl (Spofa); Revanil (Roche)
Percent Composition: C 63.42%, H 6.65%, N 12.33%, O 17.60%
Properties: Prisms from ethanol, mp 200° (dec). [a]D20 +288° (c = 0.5 in methanol). uv max (methanol): 313 nm. LD50 i.v. in mice: 14.4 mg/kg (Votava, Lamplova).
Melting point: mp 200° (dec)
Optical Rotation: [a]D20 +288° (c = 0.5 in methanol)
Absorption maximum: uv max (methanol): 313 nm
Toxicity data: LD50 i.v. in mice: 14.4 mg/kg (Votava, Lamplova)
Therap-Cat: Antimigraine; prolactin inhibitor; antiparkinsonian.
Keywords: Antimigraine; Dopamine Receptor Agonist; Prolactin Inhibitor.
产品链接: 18016-80-3››

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