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Tenapanor CAS# 1234423-95-0

Tenapanor, also known as AZD-1722 and RDX 5791, is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects. Tenapanor is currently in clinical trials.
📌 参考资料/链接:
Reference: Richter, Jindrich; Dammer, Ondrej; Krejcik, Lukas; Hejtmankova, Ludmila; Lustig, Petr; Dousa, Michal. Preparation of tenapanor free base and its salts. Assignee Zentiva K.S., Czech Rep. WO 2019091503. (2019).

📄 详细内容

CAS No. 1234423-95-0 Tenapanor synthetic routes


Richter, Jindrich; Dammer, Ondrej; Krejcik, Lukas; Hejtmankova, Ludmila; Lustig, Petr; Dousa, Michal. Preparation of tenapanor free base and its salts. Assignee Zentiva K.S., Czech Rep. WO 2019091503. (2019).
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