Moxidectin CAS# 113507-06-5 莫西菌素
Moxidectin is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms. Moxidectin is a semisynthetic derivative of nemadectin which is produced by fermentation by Streptomyces cyano-griseus. This Streptomyces species was discovered in a soil sample from Australia in the late 1980s collected by an agronomist working for the American Cyanamid company.
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Reference: Beddall, Nicola E.; Howes, Peter D.; Ramsay, Michael V. J.; Roberts, Stanley M.; Slawin, Alexandra M. Z.; Sutherland, Derek R.; Tiley, Edward P.; Williams, David J. Chemical transformations of S541 factors (A)-(D): preparation and reactions of the 23-ketones. Tetrahedron Letters. Volume 29. Issue 21. Pages 2595-8. Journal. (1988).
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CAS No. 113507-06-5 莫西菌素Moxidectin synthetic routes

Beddall, Nicola E.; Howes, Peter D.; Ramsay, Michael V. J.; Roberts, Stanley M.; Slawin, Alexandra M. Z.; Sutherland, Derek R.; Tiley, Edward P.; Williams, David J. Chemical transformations of S541 factors (A)-(D): preparation and reactions of the 23-ketones. Tetrahedron Letters. Volume 29. Issue 21. Pages 2595-8. Journal. (1988).
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