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Aminolevulinic Acid Hydrochloride–5 CAS# 5451-09-2 5-氨基乙酰丙酸盐酸盐

Aminolevulinic acid, also known as ALA, is a topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect. In 1999, FDA approved this drug for for actinic keratosis.
📌 参考资料/链接:
Shrestha-dawadi, Prativa Bade; Lugtenburg, Johan. Preparation of [1,2,3,4,5-13C5]-5-amino-4-oxopentanoic acid (ALA) - design of a synthetic scheme to prepare any 13C- and 15N-isotopomer with high isotopic enrichment. European Journal of Organic Chemistry. Issue 23. Pages 4654-4663. 2003.

📄 详细内容

CAS No. 5451-09-2 5-氨基乙酰丙酸盐酸盐Aminolevulinic Acid Hydrochloride–5 synthetic routes


Shrestha-dawadi, Prativa Bade; Lugtenburg, Johan. Preparation of [1,2,3,4,5-13C5]-5-amino-4-oxopentanoic acid (ALA) - design of a synthetic scheme to prepare any 13C- and 15N-isotopomer with high isotopic enrichment. European Journal of Organic Chemistry. Issue 23. Pages 4654-4663. 2003.
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