Lactitol CAS# 585-86-4 乳糖醇

Lactitol is a synthetic disaccharide polyol derived from lactose, used primarily as an osmotic laxative and low-calorie sweetener. In vitro studies demonstrate that it resists hydrolysis by human small intestinal enzymes but undergoes fermentation by colonic bacteria, producing short-chain fatty acids and gases that contribute to its pharmacological effects. In vivo, oral administration increases stool frequency and water content via osmotic action in the colon, while clinical studies confirm its efficacy in managing chronic constipation and hepatic encephalopathy with generally good tolerability.