Brexanolone CAS# 516-54-1 5alpha-孕甾-3alpha-醇-20-酮
Brexanolone, also known as 3a5a-Allopregnanolone; Allotetrahydroprogesterone and Allopregnanolone, is a GABA(A) receptor modulator potentially for the treatment of epilepsy and depression. Brexanolone was approved in 3/19/201 9to treat postpartum depression (PPD) in adult women.
📌 参考资料/链接：
MacNevin, Christopher J.; Atif, Fahim; Sayeed, Iqbal; Stein, Donald G.; Liotta, Dennis C. Development and Screening of Water-Soluble Analogues of Progesterone and Allopregnanolone in Models of Brain Injury. Journal of Medicinal Chemistry. Volume 52. Issue 19. Pages 6012-6023. Journal. (2009).
MacNevin, Christopher J.; Atif, Fahim; Sayeed, Iqbal; Stein, Donald G.; Liotta, Dennis C. Development and Screening of Water-Soluble Analogues of Progesterone and Allopregnanolone in Models of Brain Injury. Journal of Medicinal Chemistry. Volume 52. Issue 19. Pages 6012-6023. Journal. (2009).
📄 详细内容
CAS No. 516-54-1 5alpha-孕甾-3alpha-醇-20-酮Brexanolone synthetic routes
MacNevin, Christopher J.; Atif, Fahim; Sayeed, Iqbal; Stein, Donald G.; Liotta, Dennis C. Development and Screening of Water-Soluble Analogues of Progesterone and Allopregnanolone in Models of Brain Injury. Journal of Medicinal Chemistry. Volume 52. Issue 19. Pages 6012-6023. Journal. (2009).
产品链接: CAS No. 516-54-1 ››
MacNevin, Christopher J.; Atif, Fahim; Sayeed, Iqbal; Stein, Donald G.; Liotta, Dennis C. Development and Screening of Water-Soluble Analogues of Progesterone and Allopregnanolone in Models of Brain Injury. Journal of Medicinal Chemistry. Volume 52. Issue 19. Pages 6012-6023. Journal. (2009).
产品链接: CAS No. 516-54-1 ››