Etravirine CAS# 269055-15-4 依曲韦林
Etravirine, also known as TMC 125 and R 165335, is a drug used for the treatment of HIV. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It was also approved in 2008. Etravirine, in combination with other anti-retrovirals, is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in antiretroviral treatment-experienced adult patients, who have evidence of viral replication and HIV-1 strains resistant to a non-nucleoside reverse transcriptase inhibitor (NNRTI) and other antiretroviral agents.
📌 参考资料/链接：
Process for the preparation of 4- [6-amino-5-bromo-2- [(4-cyanophenyl) amino]-4-pyrimidinyl]oxy]-3.5-dimethylbe nzonitrile (Etravirine); Rajan, Srinivasan Thirumalai; Eswaraiah, Sajja; Gutta, Madhusudhan; Peri, Seetha Rama Sarma; Assignee MSN Laboratories Private Limited, India; 2016; Patent Information; Apr 21, 2016; WO 2016059646 A2
Process for the preparation of 4- [6-amino-5-bromo-2- [(4-cyanophenyl) amino]-4-pyrimidinyl]oxy]-3.5-dimethylbe nzonitrile (Etravirine); Rajan, Srinivasan Thirumalai; Eswaraiah, Sajja; Gutta, Madhusudhan; Peri, Seetha Rama Sarma; Assignee MSN Laboratories Private Limited, India; 2016; Patent Information; Apr 21, 2016; WO 2016059646 A2
📄 详细内容
CAS No. 269055-15-4 依曲韦林Etravirine synthetic routes
Process for the preparation of 4- [6-amino-5-bromo-2- [(4-cyanophenyl) amino]-4-pyrimidinyl]oxy]-3.5-dimethylbe nzonitrile (Etravirine); Rajan, Srinivasan Thirumalai; Eswaraiah, Sajja; Gutta, Madhusudhan; Peri, Seetha Rama Sarma; Assignee MSN Laboratories Private Limited, India; 2016; Patent Information; Apr 21, 2016; WO 2016059646 A2
产品链接: CAS No. 269055-15-4 ››
Process for the preparation of 4- [6-amino-5-bromo-2- [(4-cyanophenyl) amino]-4-pyrimidinyl]oxy]-3.5-dimethylbe nzonitrile (Etravirine); Rajan, Srinivasan Thirumalai; Eswaraiah, Sajja; Gutta, Madhusudhan; Peri, Seetha Rama Sarma; Assignee MSN Laboratories Private Limited, India; 2016; Patent Information; Apr 21, 2016; WO 2016059646 A2
产品链接: CAS No. 269055-15-4 ››