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Fezolinetant CAS# 1629229-37-3 非唑奈坦

Fezolinetant, also known as ESN-364, is Neurokinin-3 (NK-3) receptor antagonist which has been optimized for use in women’s health, and is being developed for sex-hormone related disorders such as endometriosis, polycystic ovarian syndrome and uterine fibroids. Fexolinetant allows modulation of the hypothalamic-pituitary gonadal axis with a selective action on hormones relevant to disease. The agent is expected to have greater tolerability than competing products which target GnRH (Gonadotropin-releasing hormone).
📌 参考资料/链接:
Optimization of Novel Antagonists to the Neurokinin-3 Receptor for the Treatment of Sex-Hormone Disorders (Part II)By: Hoveyda, Hamid R.; et alACS Medicinal Chemistry Letters (2015), 6(7), 736-740

📄 详细内容

CAS No. 1629229-37-3 非唑奈坦Fezolinetant synthetic routes


Optimization of Novel Antagonists to the Neurokinin-3 Receptor for the Treatment of Sex-Hormone Disorders (Part II)By: Hoveyda, Hamid R.; et alACS Medicinal Chemistry Letters (2015), 6(7), 736-740
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