Amprenavir CAS# 161814-49-9 安普那韦
Amprenavir (original brand name Agenerase, GlaxoSmithKline) is a protease inhibitor used to treat HIV infection. The mechanism of action of amprenavir is as a HIV Protease Inhibitor and Cytochrome P450 3A4 Inhibitor. It was approved by the Food and Drug Administration on April 15, 1999, for twice-a-day dosing instead of needing to be taken every eight hours.
📌 参考资料/链接:
Kim, B. Moon; Bae, Sung Jin; So, Soon Mog; Yoo, Hyun Tae; Chang, Sun Ki; Lee, Jung Hwan; Kang, JaeSung. Synthesis of a chiral aziridine derivative as a versatile intermediate for HIV protease inhibitors. Organic Letters. Volume 3. Issue 15. Pages 2349-2351. 2001.
📄 详细内容
CAS No. 161814-49-9 安普那韦Amprenavir synthetic routes

Kim, B. Moon; Bae, Sung Jin; So, Soon Mog; Yoo, Hyun Tae; Chang, Sun Ki; Lee, Jung Hwan; Kang, JaeSung. Synthesis of a chiral aziridine derivative as a versatile intermediate for HIV protease inhibitors. Organic Letters. Volume 3. Issue 15. Pages 2349-2351. 2001.
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