Pitavastatin (Calcium) CAS# 147511-69-1 / 147526-32-7 匹伐他汀
Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting Nox. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187.
📌 参考资料/链接：
Yagi, Yusuke; Kimura, Hiroyuki; Arimitsu, Kenji; Ono, Masahiro; Maeda, Kazuya; Kusuhara, Hiroyuki; Kajimoto, Tetsuya; Sugiyama, Yuichi; Saji, Hideo. The synthesis of [18F]pitavastatin as a tracer for hOATP using the Suzuki coupling. Organic & Biomolecular Chemistry. Volume 13. Issue 4. Pages 1113-1121. 2015.
Yagi, Yusuke; Kimura, Hiroyuki; Arimitsu, Kenji; Ono, Masahiro; Maeda, Kazuya; Kusuhara, Hiroyuki; Kajimoto, Tetsuya; Sugiyama, Yuichi; Saji, Hideo. The synthesis of [18F]pitavastatin as a tracer for hOATP using the Suzuki coupling. Organic & Biomolecular Chemistry. Volume 13. Issue 4. Pages 1113-1121. 2015.
📄 详细内容
CAS No. 147511-69-1 / 147526-32-7 匹伐他汀Pitavastatin (Calcium) synthetic routes
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Yagi, Yusuke; Kimura, Hiroyuki; Arimitsu, Kenji; Ono, Masahiro; Maeda, Kazuya; Kusuhara, Hiroyuki; Kajimoto, Tetsuya; Sugiyama, Yuichi; Saji, Hideo. The synthesis of [18F]pitavastatin as a tracer for hOATP using the Suzuki coupling. Organic & Biomolecular Chemistry. Volume 13. Issue 4. Pages 1113-1121. 2015.
产品链接: CAS No. 147511-69-1 / 147526-32-7 ››
Yagi, Yusuke; Kimura, Hiroyuki; Arimitsu, Kenji; Ono, Masahiro; Maeda, Kazuya; Kusuhara, Hiroyuki; Kajimoto, Tetsuya; Sugiyama, Yuichi; Saji, Hideo. The synthesis of [18F]pitavastatin as a tracer for hOATP using the Suzuki coupling. Organic & Biomolecular Chemistry. Volume 13. Issue 4. Pages 1113-1121. 2015.
产品链接: CAS No. 147511-69-1 / 147526-32-7 ››