Alcaftadine CAS# 147084-10-4 阿卡他定
Alcaftadine is used to prevent eye irritation brought on by allergic conjunctivitis. It is a H1 histamine receptor antagonist. It was approved by the U.S. Food and Drug Administration in 2010 under the trade name Lastacaft. Alcaftadine is an antagonist at three of the histamine receptors (1, 2 and 4). The main indication for Alcaftadine is for prevention of allergic conjunctivitis. By blocking these four receptors, Alcaftadine has been shown to significantly reduce the effects of allergens.
📌 参考资料/链接:
Ponnaiah, Ravi; Hashmi, Arshad Moosa; Neela, Praveen Kumar; Seemala, Dhanunjaya Naidu; Mokka, Raviteja; Lahoti, Anandkumar Madanlal; Deepthi, V. P. S. S.; Saradhi, G. Srinivas Pardha. A process for the preparation of alcaftadine (Assignee Neuland Laboratories Limited, India). 2014 Patent Information. Jun 05, 2014. WO 2014083571 A1
📄 详细内容
CAS No. 147084-10-4 阿卡他定Alcaftadine synthetic routes

Ponnaiah, Ravi; Hashmi, Arshad Moosa; Neela, Praveen Kumar; Seemala, Dhanunjaya Naidu; Mokka, Raviteja; Lahoti, Anandkumar Madanlal; Deepthi, V. P. S. S.; Saradhi, G. Srinivas Pardha. A process for the preparation of alcaftadine (Assignee Neuland Laboratories Limited, India). 2014 Patent Information. Jun 05, 2014. WO 2014083571 A1
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