新产品编号:1829301

Chemical Name: 3-(1,3-Benzodioxol-5-yl)propionic acid N'-[4-(dimethylamino)benzylidene]hydrazide
项目整合开发状态: Preclinical
项目研究机构: Universidade Federal do Rio de Janeiro (Originator)
合成路线:The regioselective hydroboration of safrole (I),followed by oxidative work-up,furnished the primary alcohol (II).Jones oxidation of alcohol (II) yielded carboxylic acid (III),which was subsequently esterified by means of MeOH and H2SO4.Treatment of methyl ester (IV) with hydrazine gave hydrazide (V).This was finally condensed with 4-(dimethylamino)benzaldehyde (VI) to provide the title acyl hydrazone.