SC-22716
Chemical Name: 1-[2-(Biphenyl-4-yloxy)ethyl]pyrrolidine
项目整合开发状态: Preclinical
项目研究机构: Pfizer (Originator)
合成路线:The title compound was prepared by alkylation of 4-phenylphenol (I) with 1-(2-chloroethyl)pyrrolidine.HCl (II) in the presence of NaH in hot DMF.
📌 参考资料/链接：
参考文献标题:Structure-activity relationship studies on 1-[2-(4-phenylphenoxy)ethyl]pyrrolidine (SC-22716),a potent inhibitor of leukotriene A4 (LTA4) hydrolase
文献作者:Penning,T.D.; Chandrakumar,N.S.; Chen,B.B.; Chen,H.Y.; Desai,B.N.; Djuric,S.W.; Docter,S.H.; Gasiecki,A.F.; Haack,R.A.; Miyashiro,J.M.; Russell,M.A.; Yu,S.S.; Corley,D.G.; Durley,R.C.; Kilpatrick,B.F.; Parnas,B.L.; Askonas,L.J.; et al.
参考来源:J Med Chem 2000,43(3),721