新产品编号:1796079

Chemical Name: 2-[2-(Diethylamino)ethyl]-5-methyl-2H-pyrido[3',4':5,6]thiopyrano[4,3,2-cd]indazole
项目整合开发状态: Biological Testing
项目研究机构: Novuspharma (Originator)
合成路线:Condensation of 4-chloronicotinic acid (I) with 5-chloro-2-methylthiophenol (II) led to thioether (III).Treatment of (III) with thionyl chloride,followed by Friedel-Crafts cyclization of the resulting acid chloride (IV) with AlCl3 in nitrobenzene at 100 C afforded the tricyclic compound (V).Finally,heating of (V) with N-(2-dimethylaminoethyl)hydrazine (VI) furnished the title compound.